Vymada 100 (Sacubitril/Valsartan 100 mg)

Vymada 100 – A Modern Treatment for Heart Failure

Heart failure is one of the most pressing health conditions worldwide, affecting millions of people every year. With advancements in cardiovascular medicine, new treatment options are now available that improve both survival and quality of life. Vymada 100 is a breakthrough therapy that combines two powerful agents—Sacubitril and Valsartan—to help patients with chronic heart failure manage their condition more effectively.

What is Vymada 100?

Vymada 100 is a prescription medication containing a fixed-dose combination of Sacubitril (100 mg) and Valsartan (100 mg). It belongs to a class of drugs known as ARNIs (Angiotensin Receptor-Neprilysin Inhibitors), which represent a newer, more effective alternative to traditional ACE inhibitors and ARBs for treating certain types of heart failure.

Vymada 100 (Sacubitril/Valsartan 100 mg) is a proven, effective, and modern treatment for chronic heart failure. By combining the benefits of neprilysin inhibition and angiotensin receptor blockade, it not only improves symptoms but also significantly reduces the risk of hospitalization and cardiovascular death.

If you’ve been prescribed Vymada, take it exactly as directed by your doctor and schedule regular follow-ups to monitor your progress. Managing heart failure requires a combination of medication, lifestyle changes, and professional medical care.

Vymada 100 is widely prescribed to patients with:

• Chronic Heart Failure (HFrEF – Heart Failure with reduced Ejection Fraction)
• Patients who continue to have symptoms despite standard therapy
• Those at risk of hospitalization due to worsening heart failure

How Does Vymada 100 Work?

Vymada 100 works through its dual mechanism of action:

1. Sacubitril (Neprilysin Inhibitor):

• • Prevents the breakdown of natriuretic peptides.
  • These peptides help dilate blood vessels, reduce fluid buildup, and lower blood pressure.
  • This improves heart efficiency and reduces strain.

2. Valsartan (Angiotensin II Receptor Blocker – ARB):

• • • Blocks the harmful effects of angiotensin II, a hormone that tightens blood vessels and raises blood pressure.
    • Reduces the risk of further heart damage, lowers blood pressure, and decreases the likelihood of hospitalization.

Together, Sacubitril/Valsartan 100 mg significantly improves survival rates, reduces hospital visits, and enhances overall patient well-being compared to older treatments, such as enalapril.

Benefits

Patients prescribed may experience:

• Improved heart function and reduced workload on the heart
• Lower risk of cardiovascular-related hospitalization
• Better quality of life with reduced symptoms (fatigue, breathlessness, swelling)
• Lower blood pressure and improved circulation
• Reduced long-term risk of heart failure progression

According to the PARADIGM-HF trial (published in the New England Journal of Medicine), patients treated with Sacubitril/Valsartan had a 20% reduction in cardiovascular mortality compared to enalapril.

Dosage

The dosage of Vymada 100 mg varies depending on the patient’s health status and previous treatments. Generally:

• The usual starting dose is Vymada 50 mg twice daily, which may be increased to this dose twice daily as tolerated.
• Some patients may require higher doses (200 mg twice daily) under medical supervision.
• It is taken orally, with or without food.
• Patients switching from ACE inhibitors must wait at least 36 hours before starting Vymada to avoid life-threatening reactions like angioedema.

Always follow your doctor’s prescription and never adjust your dosage without consulting them.

Side Effects

Like all medications, Vymada 100 may cause side effects in some patients. The most commonly reported include:

• Low blood pressure (hypotension)
• Dizziness or lightheadedness
• Elevated potassium levels (hyperkalemia)
• Kidney function impairment
• Cough
• Fatigue

Serious but rare side effects:

• Angioedema (swelling of face, lips, throat) – requires immediate emergency attention.
• Severe kidney issues or dangerously high potassium levels.

If you experience any unusual or severe symptoms while taking Sacubitril/Valsartan 100 mg, contact your healthcare provider immediately.

Drug Interactions

Vymada 100 may interact with certain medications, including:

• ACE inhibitors (risk of angioedema)
• Potassium supplements or potassium-sparing diuretics
• NSAIDs (such as ibuprofen, naproxen)
• Lithium (increased toxicity risk)
• Blood pressure medications

Always inform your doctor about all medicines and supplements you are taking before starting Vymada 100.

Who Should Not Take Vymada 100?

Vymada is not suitable for everyone. It should be avoided in:

• Patients with severe liver impairment
• Pregnant women (may harm the unborn baby)
• Breastfeeding mothers
• Patients with a history of angioedema
• Those with extremely low blood pressure or advanced kidney disease

Storage

• Store Vymada 100 mg at room temperature (20–25°C).
• Keep away from moisture and direct sunlight.
• Store in the original packaging.
• Keep out of reach of children.

FAQs

1. What is Vymada 100 used for?

Vymada 100 (Sacubitril/Valsartan 100 mg) is used to treat chronic heart failure with reduced ejection fraction (HFrEF), helping reduce hospitalizations and improve survival.

2. How long does it take for Vymada 100 to work?

Many patients notice improvements in symptoms, such as breathing and fatigue, within a few weeks, but the long-term benefits are more pronounced with consistent use over several months.

3. Can I take Vymada 100 with other heart medications?

Yes, but it depends on your doctor’s recommendation. Vymada is often used alongside beta-blockers, diuretics, or aldosterone antagonists, but not with ACE inhibitors.

4. Is Vymada 100 safe for elderly patients?

Yes, it can be prescribed to elderly patients with heart failure, but dosage adjustments may be needed depending on kidney function and blood pressure.

5. Can pregnant women take Vymada 100?

No. Vymada is contraindicated during pregnancy, as it may cause serious harm to the unborn baby.

6. What should I do if I miss a dose?

Take the missed dose as soon as you remember, unless it’s almost time for your next dose.  Making up for a missed dose should not be done by double-dosing.

7. Is Vymada 100 available online?

Yes, you can order Vymada 100 mg from trusted online pharmacies such as Lovemymed.com with a valid prescription.